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It works through several mechanisms: Enhances insulin secretion from pancreatic beta cells in a glucose-dependent manner Suppresses glucagon release , reducing hepatic glucose production Slows gastric emptying , which prolongs satiety and reduces appetite Acts on brain appetite centers to decrease food intake and promote weight loss Semaglutide is administered as a once-weekly subcutaneous injection (Ozempic, Wegovy) or as a daily oral tablet (Rybelsus)

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A Cardiorespiratory Digital Twin can ingest wearable data (heart-rate variability, sleep architecture, training load), biomarker data (inflammatory markers, MOTS-c levels, collagen-turnover markers), and genomic data (connective-tissue gene variants, mitochondrial DNA haplogroup) to create a continuously updated model of an individual athlete's physiological state