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It acts through the GPCR receptors VPAC1 and VPAC2, activating cAMP-related signaling pathways that regulate vascular tone, immune balance, secretion mechanisms, and neuronal survival

By combining SLU-PP-332 and 5-Amino-1MQ, researchers can investigate multi-pathway interactions and potential synergistic effects

Potential tumor promotion : Given its angiogenic properties, there is theoretical concern it could contribute to tumor growth or neovascularization in certain contexts

Banks and colleagues injected DSIP and four analogues intravenously into dogs and measured DSIP-like material in cerebrospinal fluid sampled from the posterior fossa over 60 minutes