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An opioid overdose is characterized by Decreased consciousness, somnolence Small pupils Fatigue Slow speech Calmness Cold sensation Anesthesia Coma Urinary retention Respiratory depression, respiratory failure Hypoxia, cyanosis, grayish pale skin Bradycardia Hypotension Circulatory collapse Life-threatening overdose can occur after injection as well as smoking but is much more common after injections

The 2001 amendment to the Childrens Act prohibits children under 18 from performing any work, involving contact with any hazardous substance, article or process,[57] and the Environmental Management Act of 2002 defines a hazardous substance as any substance, whether solid, liquid, or gaseous, or any organism which is injurious to human health or the environment.[58] Statutory Instrument 12 of 2007 outlines the Environmental Management Acts regulations and specifically includes pesticides among the substances considered hazardous.[59] In its response to Human Rights Watch, the government confirmed that the use of chemicals would be considered hazardous work for children.[60] Mercy, a 12-year-old child tobacco worker in Mashonaland Central, described how she applied pesticides to the small-scale farms where she worked: We take the chemical and put it in the water