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Nevertheless, to minimize any confounding effects from solvent interactions, the concentration of DMSO, known to disrupt membrane integrity, was maintained below 1% in all working solutions, in accordance with the guidelines of the Clinical and Laboratory Standards Institute and previous findings by Tuner et al

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doi: 10.1371/journal.pone.0304253 73 PorcariS.BenechN.Valles-ColomerM.SegataN.GasbarriniA.CammarotaG.et al

Inhibition of UBA6 by inosine augments tumour immunogenicity and responses