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The difference between these two forms is that apo-Lf does not include any bound Fe 3+ ion, but holo-Lf is in the form of a complex bound with Fe 3+

This process can occur either aerobically or anaerobically, the latter leading to lactate production and release

In addition, we review how to best educate patients to encourage their adherence to the gout therapeutic program, a key aspect of the success of management