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Similarly, a meta-analysis of nine observational studies in older adults found low serum vitamin B 12 concentration to be associated with increased risk for depression, with significant association only in women (100)

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As FBXO22 is an E3 ubiquitin ligase, the BPC157-FBXO22 complex likely regulates BACH1 protein levels by modulating its ubiquitination-mediated degradation

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