2.3.2 Black cohosh Black cohosh ( Actaea racemosa ) uses in managing menopausal symptoms has also been highlighted for breast cancer relevant to its possible symptomatic improvement of vasomotor symptoms such as hot flushes, night sweats, and mood swings reported in women undergoing tamoxifen or amrastase inhibitor therapy where oestrogen depleting would increase menopausal complaints (97)
Some studies have reported that, in patients with EMS, both normal endometrial stromal cells (NESCs) and ectopic endometrial stromal cells (EESCs) exhibit significantly increased Fibulin-1 expression, which confers ferroptosis resistance on EESCs by inhibiting ferroptosis (27)
Pompura SL, Wagner A, Kitz A, LaPerche J, Yosef N, Dominguez-Villar M, et al
These diseases, including atherosclerosis, myocardial infarction, cardiac hypertrophy, and heart failure, are closely linked to genetic, metabolic, and environmental factors