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4 Indeed, many patients mistake it for a cold sore and often other people don't comment for fear of causing offence, thus it can proliferate easily without early recognisable symptoms or pain (see Figs 1-2)

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One reason the levels of 1a-d are higher herein is that we used the harsher 50 puff replication study puffing regimen, which the researchers performing the latter study had modified 4 (without explanation) from our original milder 10 puff experiments

The importance of these health warnings as a source of information varies across gender