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radiosensitizing formulations Hydrogels can be strategically engineered to serve complementary yet divergent roles in radiotherapy, functioning either as radioprotective shields or radiosensitizing enhancers, depending on therapeutic objectives [123, 147, 148]

Furthermore, several studies were conducted on various classes and isoforms of GSTs to obtain informations about their association with increased risk for the development of the disease 47,50

N-acetylcysteine chemoprotection without decreased cisplatin antitumor efficacy in pediatric tumor models

40 , 41 However, high doses of glutathione for prolonged periods may cause chronic toxicity and carry some risks like zinc depletion, hypersensitivity, drug interactions, teratogenicity, etc