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Popular in early 20th century America, cigarette silks were produced by many tobacco companies as free accompaniments to cigarette packets

6,7 From the patient perspective, potential barriers include long waits for appointments with a primary care provider to receive a prescription for a quit-smoking medication (e.g., an average of 29.3 days to see a family medicine physician), 9 distance needed to travel to access a provider, and limited availability of physician appointments outside of typical working hours

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[8] The nitrosonium group forms from nitrous acid (HNO 2 ) under acidic conditions present in the tobacco curing process