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NHS laboratories generally define deficiency as a serum B12 below approximately 148 pmol/L (equivalent to roughly 200 ng/L or pg/mL), though reference ranges vary between laboratories and results should always be interpreted in the context of local ranges and the patient's clinical presentation

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For older adults, especially if their diet is limited, supplemental B12 is usually recommended.[ref] Choosing the right type of vitamin B12 for your genes: Access this content: An active subscription is required to access this content