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Age-related decrease: GHK-Cu levels naturally decrease from ~200ng in youth to ~80ng by age 60, contributing to visible signs of aging such as reduced firmness and vitality

In research settings, it is studied for its ability to stimulate the pituitary glands natural growth hormone secretion

"Clinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation"

Free Radic Biol Med 47:13291338 Kowalec P, Grynberg M, Pajak B, Socha A, Winiarska K, Fronk J, Kurlandzka A (2015) Newly identified protein Imi1 affects mitochondrial integrity and glutathione homeostasis in Saccharomyces cerevisiae