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In chronic wounds, there is excessive secretion of inflammatory mediators, such as cytokines and matrix metalloproteinases (MMPs), which degrade growth factors and the extracellular matrix (ECM), further impairing healing

Cyanocobalamin is however very straightforward and cheap to manufacture and is particularly stable

Forde and Roberts (2014) highlighted the contribution of GLRs to Ca 2+ flux during immune activation, emphasizing their importance as molecular hubs linking environmental cues with intracellular responses

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