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Bone Healing: Preclinical research has investigated: Acceleration of fracture healing in rodent models Improved callus formation and bone density Enhanced integration of bone grafts Potential effects on osteoblast and osteoclast activity For dogs recovering from fracture repair surgeries or orthopedic procedures, these mechanisms could theoretically support healing, though clinical evidence specific to canines is limited

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In the liver, DCs not only participate in inducing immune tolerance and regulating T cell responses (Tong et al., 2023), but also modulate intrahepatic homeostasis and the fibrotic process ( In healthy livers, DCs are relatively sparse and exhibit limited capabilities in antigen phagocytosis and T cell stimulation

[DOI] [PubMed] [Google Scholar] 56.Smrkolj P., Pograjc L., Hlastan-Ribi C., Stibilj V