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Should we be squeamish about doing so for other things

Overall, sweeteners are a popular addition to many vape juices, providing a diverse range of flavours to satisfy different preferences, however it is worth noting that disposable vape pens and other nicotine salt e-liquids typically contain 3 to 4 times the amount of flavourings used in freebase nicotine liquids, which likely means vaping with nic salts produces more volatile compounds (as does vaping at higher power), indicating that using freebase nicotine and vaping with a low power vape could be the safest way to vape

Limitations The overview approach we used for interventions other than e-cigarettes comes with limitations, as we relied on what was reported in the Cochrane systematic reviews