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Peptides are typically administered through subcutaneous injections, which can be done conveniently at home after proper instruction, or through other methods like nasal sprays, creams, or tablets, depending on the specific peptide and protocol

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As shown in Supplementary Figure S1, Pearson correlation analysis showed that inter-group between the M and C groups had lower correlation, while the intra-group in the M or C group had higher correlation (Supplementary Figure S1A)