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Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)

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Domestic shipping: EU UK USA AU 57 days International shipping: 714 days 4 publications found Last 10 years 3 most recent shown Source: PubMed / NCBI Last 10 years Refreshed every 24 hours For research reference only not clinical guidance