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doi: 10.1002/j.1875-9114.1996.tb02920.x

Through incubation in fresh mouse serum, the results showed that the peptide modified with a C18 fatty diacid chain has a three-fold longer half-life in the serum compared to the peptide modified with a C10 fatty diacid chain

Methionine is first converted into S-adenosylmethionine (SAM), which serves as a methyl donor for various methylation reactions, including the synthesis of cysteine