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This activation, driven by TMEM19 protein binding, was accompanied by the upregulation of angiogenic cytokines and growth factors, as well as neuroprotection, suggesting a new therapeutic function for erucamide in retinal diseases

Under conditions of chronically low corticosterone, insufficient MR/GR activation may contribute to reduced BDNF transcription through impaired cAMP response element-binding protein (CREB)-dependent regulation

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