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Hypothesis to be tested In Nepalese women, daily supplementation of 50 g vitamin B 12 from early pregnancy, not later than week 15, and until 6 months postpartum, improves linear and ponderal growth as well as cognitive, language and/or motor scores of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) in their infants

One study showed that the abundance of the CUL4B-PRC2 complex increases in response to high-glucose stimulus and affects intracellular Ca 2+ by decreasing Cav1.2 expression ( 2+ was fast, suggesting that BHBA might directly affect the opening and closing of L-type VSCCs

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