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NO is involved in normal cell signaling, contributing to the regulation of various physiological functions [141, 142] including activation of soluble guanylyl cyclase (sGC) which generates cyclic GMP (cGMP) [143]

Thakkar KN, Rsler L, Wijnen JP, Boer VO, Klomp DW, Cahn W, et al

The fact that there are several plants used in African traditional medicine, for which little information is available on their constituents, can increase the risk of adverse reactions, particularly in vulnerable groups such as older adults, children, and pregnant women (Mensah et al., 2019

A 1000mg oral dose might deliver 100150mg to plasma if you're lucky