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7, 8, 9, 10 As an example, mast cells are involved in autoimmune disorders and many of the proinflammatory and tissue destructive mediators produced by these cells have been directly implicated in the pathogenesis of rheumatoid arthritis and other rheumatic diseases

16, Sonthalia, Sidharth, et al

Cardioprotection / cytoprotection Researched in animal studies for possible cytoprotective effects on cardiac and other tissue

ROS can directly attack DNA, causing oxidative damage (Taniguchi et al., 2012), including base damage and single-strand breaks, which can cause DNA to mutate and change structurally (Roy, 2014)