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These compounds have been investigated in combination for their complementary and mechanistically distinct receptor pathway interactions, with research examining their combined effects on hypothalamic energy substrate regulation and pancreatic hormone secretion dynamics

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Injections pose risks such as infection, vein irritation, anaphylaxis, and dosage errors

Thus, the neuroprotective effects exhibited by curcumin in preclinical TBI models can be attributed to its ability to modulate oxidative stress, neuroinflammation, mitochondrial dysfunction, and autophagy