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doi:10.1016/j.fertnstert.2013.08.032

In the UK, intramuscular (IM) administration is standard practice for hydroxocobalamin, though subcutaneous (SC) may be used if specifically advised by your healthcare provider and following appropriate training

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However, clinical research commonly tests doses ranging from 250 to 600 milligrams per day, with the most effective results often observed at 500600 milligrams daily taken consistently for at least one to two months