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Chemokines in target cell tissues can also induce directed cell migration, initiate signal pathways, and monitor cytoskeletal rearrangment and adhesion (91)

In the case of study LOAZ, the use of healthy individuals necessitated that only very low (subtherapeutic), single OLAI doses could be studied because healthy individuals usually cannot tolerate therapeutic doses of antipsychotics (Cutler, 2001)