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APVMA Approval Number: 52631 Dosage Rates 100mL multi-dose vial administration of 5mL-20mL in acutely diseased animals (repeat daily if required)

Given that absorption through the gastrointestinal tract can be impaired in some individuals, injections provide a reliable alternative to oral supplements

Anaemia is a common cause of B12 or folate deficiency where there are fewer red blood cells or a lower amount of haemoglobin, which helps the blood carry oxygen around the body

Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults