In terms of systemic infection and prognosis, although the polymorphism of Dectin-1/CARD9 is not consistently associated with the susceptibility to Candida bloodstream infection, the responses of the heterozygous Y238X carriers to cytokines in vitro are weakened, which may affect the inflammatory regulation and prognosis of severe infections (Rosentul et al., 2011)
Kumbrink J, Gerlinger M, Johnson JP
Am J Cancer Res 11:23692385 Castao M, Toms-Prez S, Gonzlez-Cant E, Aghababyan C, Mascars-Martnez A, Santonja N, Herreros-Pomares A, Oto J, Medina P, Gtte M et al (2023) Neutrophil extracellular traps and cancer: trapping our attention with their involvement in ovarian Cancer
Precision Medicine for Crohns Disease Precision medicine uses tools like genetics, biomarker testing, and patient history to create individualized treatment plans