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VIP and immune cell modulation VIP interacts with multiple immune cells through specific receptors (VPAC-1, VPAC-2, CRTH2, and PAC1) expressed on eosinophils, mast cells, neutrophils, lymphocytes, dendritic cells, NK cells, and macrophages

doi: 10.1002/glia.23510 151 AkiyamaHBargerSBarnumSBradtBBauerJColeGMet al

Glutathione addresses different types of pigmentation, and individual variations are involved due to: Depth of Pigmentation Hormonal Involvement Sun exposure Consistency of use Glutathione for Melasma Melasma is the most stubborn and resistant form of pigmentation in the skin