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Even though they can be commercially acquired as a cell line, being readily characterized and accessible, one disadvantage lies in the fact that they may not express all the surface molecules as primary cells do, due to the immortalization process, making them a less reliable model of the in vivo behavior [88]

doi: 10.1038/s41598-020-64849-w 118 KostenkovaK.ScaleseG.GambinoD.CransD

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