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Thats when you feel the pleasure and your brain creates the DISPOSITION for that situation, whether its drinking water, eating chocolate or lighting up a smoke

First, nicotine acts primarily through neuronal nicotinic acetylcholine receptors (nAChRs), which are ligand-gated ion channels widely distributed in both pre-and post-synaptic regions of the brain (33, 34)

In one of the first investigations of smoking in young adults, Peters and Ferris (1967b) surveyed male and female college students with a questionnaire on respiratory symptoms as well as a spirometry test

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