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To improve their efficacy and tolerance, hormonal contraceptives have suffered many changes in their composition and dosage, reducing adverse reactions such as nausea, vomiting, and headache (Wright et al., 2020)

Over time, telomeres shorten, ultimately limiting cellular replicative capacitya central feature of biological aging

Cell cycle analyses Cell cycle analysis was carried out using the Click-iT EdU Cell Proliferation Assay Kit (ThermoFisher Scientific) according to the manufacturers instructions

*Correspondence: Yvonne Samstag [email protected] This article was submitted to T Cell Biology, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers