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When stimulated, this receptor also tells the pituitary to release GH

At physiological pH (6.57.4), dihexa exists partially in its protonated form, which increases its interaction with taste receptors

Compared with GPX1-3, GPX4 is also involved in the reduction of complex membrane-associated phospholipid hydroperoxides such as phosphatidylcholine hydroperoxide and cholesterol hydroperoxide, in addition to reacting with soluble, low molecular weight hydroperoxides such as t-butyl hydroperoxide and cumene hydroperoxide [68]