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The potential of TB-500 on angiogenesis and migration was assessed using MTT assays for cell viability, tube formation assays for angiogenesis, and wound healing assays for the migratory ability of HUVEC

Experts continue to argue over which blood values signify a vitamin B12 deficiency

Moreover, the treatment should be able to reach the central nervous system, which is a difficulty for both drugs (must cross the bloodbrain barrier or be administered intrathecally) [263] and devices (surgical access to the CNS might be required)