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The threshold intensity was manually set and kept constant, and the number of pixels was determined for 4G8-, ThS-, Iba1- and GFAP stained sections to quantify amyloid load, fibrillar burden, microglial activation and reactive astrogliosis in hippocampal (CA1, CA2, CA3 and dentate gyrus), subiculum and cortical areas (including motor, somatosensory, visual, frontal, parietal and retrosplenial cortex)

They are particularly appealing because they do not produce smoke or vapor, making them suitable for use in situations where smoking or vaping might be impractical or prohibited

In recent months, Massachusetts and other states, including Michigan, Montana, New York, Oregon, Rhode Island, Utah and Washington, have temporarily banned or restricted the sale of vaping products