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SKU: 23621342683

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Description

Festjens N, Vanden Berghe T, Vandenabeele P (2006) Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response

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The pathogenesis of OA is highly complex, involving interactions among multiple factors such as abnormal mechanical loading, age-related metabolic changes, persistent inflammatory responses, dysregulated extracellular matrix(ECM) metabolism, and genetic susceptibility