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On the other hand, excessive alcohol consumption during thiopurine treatment has been reported to cause peliosis hepatis (Martinez-Chantar et al., 2002), which is essential to the catalytic activity of TPMT (Lysaa et al., 1996)

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Instead of vasodilation inhibition, in other models, vasoconstriction is induced with angiotensin II, ET-1, or thromboxane A2, to promote ECD

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