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In principle, decreased extracellular potassium entails myocardial hyperexcitability, with the potential to develop re-entrant arrhythmias in the skeletal muscle, hyperpolarization of the resting membrane potential, and a greater-than-normal stimulus for depolarization of the membrane in order to initiate an action potential [106]

Accounts of Chemical Research, 1991, 24 9: 264-270

Risk Tier: LOW-MODERATE This rating reflects the compound's bioactive epigenetic and telomerase-related modulation activity in preclinical models and the need for proper handling to prevent accidental exposure during reconstitution

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