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Once phosphorylated and activated by PKA, hormone-sensitive lipase translocates to lipid droplets within the fat cell and begins breaking down stored triglycerides into free fatty acids and glycerol

For Asians, especially women with darker skin tones (Fitzpatrick Skin Types IV and V), clear, bright skin is considered highly desirable, and various topical, oral, or injection-based cosmetic skin-lightening agents with different mechanisms of action are widely available across Asia

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PMID: 19438432