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5.1.3 Eutectic and co-crystal innovations enhancing compound solubility Eutectic systems and co-crystal technologies provide alternative approaches for bioavailability enhancement through molecular-level modifications that improve solubility, stability, and dissolution characteristics (230)

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They are not permanent and need maintenance to sustain

doi: 10.1210/jc.2007-1290 221 BaasEMRomijnMvan der PalSMVrijlandtEJLERotteveelJFinkenMJJet al