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While it had been suggested that users of smokeless tobacco are exposed to high levels of nicotine and cancer-causing agents, there were few studies looking at those levels in people across the U.S., they write

It is a useful figure, but it is not a precise scientific estimate. Although e-cigarettes do not contain some of the more dangerous components of conventional cigarettes such as tar or carbon monoxide some potentially harmful products may be present, including certain heavy metals

states have lost USD 79.43 billion from incoming smuggled goods

Those are astonishing figures given that vaping barely existed just over a decade ago