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A recent phase 2 trial investigated the triple biased GLP-1/GIP/GCC receptors agonist retatrutide (LY3437943) in 338 patients with a mean age of 48 years and BMI of 37.3 kg/m 2 without diabetes (prediabetes in 36% participants) showing BW and WC reduction ranging from 8.7% to 24.2% and 6.5 cm to 19.6 cm in the 1 mg and 12 mg dose groups, respectively, at 48 weeks 41

Conclusion Miscarriage is the leading complication associated with pregnancy

IGF-1 LR3 (Long R3 insulin-like growth factor-1) is an engineered analog of the naturally occurring peptide hormone IGF-1, redesigned in the laboratory so that it evades the binding proteins that normally sequester and regulate native IGF-1 in circulation

Chang MX, Xiong F (2020) Astaxanthin and its effects in inflammatory responses and inflammation-associated diseases: recent advances and future directions