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Despite the complexity of TMAOs role in atherosclerosis, studies have indicated that managing TMAO through nutrition, medication, or microbiome modification may help lessen its effects and even reverse its contribution to the advancement of the disease [73, 76]

Interestingly, in this study, docked poses of the mh-Tyr-EC and mh-Tyr-CH showed positive binding free energy when interacting with copper ions while endpoint binding free energy exhibits lower negative energy values (Table S3, Fig

FDA Registration Number : 10-1-5916510 **The result varies in individuals.**

Athletes and fitness enthusiasts continue to use L-carnitine to improve their energy metabolism and, therefore, achieve their body composition goals