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A 5mg dose requires exactly 0.2mL or 20 units on a U-100 syringe

Gipp et al., 1995

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When to Seek Medical Attention Contact your healthcare provider if your headache: Becomes progressively worse Persists despite hydration and treatment Interferes significantly with normal activities Recurs after multiple infusions Seek immediate medical attention if your headache is accompanied by: Neck stiffness Fever Confusion or altered mental status Visual disturbances Severe nausea or vomiting Weakness, numbness, or difficulty speaking These symptoms may indicate a more serious complication and require prompt evaluation