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G., Wilbur, T

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This dimerization appears to induce a switch in intracellular signaling cascades in which administration of a dopamine agonist (quinpirole) alone leads to a rapid increase in Ca 2+ levels, an effect not observed in preparations expressing D2R in the absence of GHSR1a (Kern et al., 2012)

As such, plasma which was deproteinized prior to storage at 80 o C was thawed and further diluted 1:2.5 with assay buffer to produce a final dilution of 1:5 before assaying