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Therapies aimed at restoring a healthy microbiome or blocking deleterious MGBA signals (like LPS or certain bile acids) are being explored as novel ways to slow AD progression

IUBMB Life 72:18191829 Rezai-Zadeh K, Shytle D, Sun N, Mori T, Hou H, Jeanniton D, Ehrhart J, Townsend K, Zeng J, Morgan D (2005) Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice

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Main Research Findings 1) When administered to rats, DSIP was found to recover motor function following experimentally-induced strokes