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MOTS-c is a potent activator of AMPK (Adenosine Monophosphate-activated Protein Kinase)

Protects brain cells and prevents dementia

(5) Stier H, Vos E, Kenley D, Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans

This mechanism represents a fundamentally different approach to fat metabolism compared to appetite suppression (GLP-1 agonists) or direct lipolysis stimulation (growth hormone peptides)