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& Sah, R

111 And some authors have found little to no advantage of pharmacologic antidepressant treatment over placebo, psychotherapy, or exerciseall of which have much lower risk of adverse effects

Like QueD/QueD2, both FolEIA and FolEIB are members of the T-fold superfamily, 678 and are characterized by very low pairwise sequence identity and distinct oligomeric assembly states, i.e , dimer of pentamers vs a dimer of dimers double ring-shaped architectures in FolEIA and FolEIB, respectively (Figure 30A,B)