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doi: 10.3978/J.Issn.2072-1439.2015.10.63 Summary Keywords adolescent substance use, CRAFFT screener, Costa Rica, screening tool, violence, national survey Citation Lopez-Soto A, Ramirez E, Cordoba J and Montero-Zamora P (2025) Substance use risk screening and associated factors among Costa Rican secondary students: a nationally representative analysis

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Moreover, total dendritic cells, macrophages, CD4 + , and CD8 + T cells increased significantly after smoke exposure, together with an upregulation in mRNA expression of CCL9 and CCL20, two important chemokines in CD pathogenesis (19) (Figure 1)

However, this comprehensive guide aims to shed light on the potential side effects of vaping, both in the short and long term, as well as to examine the benefits of switching from smoking to vaping