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Further structural and biochemical analyses, which are clearly beyond the scope of this study, will be necessary in the future to fully decipher the role of C* in cereulide assembly

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The use of peptide therapies should prioritize evidence-based decision-making where available, careful evaluation of risks and benefits, appropriate regulatory alignment, and ongoing attention to emerging safety data (Petrou et al., 2025)

The oxidative branch produces both ribose-5-phosphate (R5P), which is precursor for nucleotide synthesis, and NADPH, which is not only required for biosynthesis reactions but also for antioxidant response function