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Emerging evidence also suggests that therapies directed at redox regulation may be more effective when combined with interventions targeting mitochondrial function and key hypoxia-induced molecular mechanisms, highlighting the importance of mechanistically guided clinical trials using standardized biomarkers and altitude-exposure protocols

However, a doctor can still use the drug for that purpose

In this study, we demonstrated that the treatment with the neuropeptide cortistatin alleviates chronic neuropathic pain in a variety of well-established preclinical models of chronic constriction and transection of the sciatic nerve and of diabetic peripheral neuropathy

Theranostics 12 , 75097531 (2022)